Biointerfaces in sensors and medical devices: challenges, materials, and solutions for biological integration

Authors

  • Inwang Edet Usoro Department of Medical Radiography and Radiation Sciences, College of Medicine, Lead City University, Ibadan, Nigeria Author
  • Robert O. Akhigbe Department of Medical Radiography and Radiation Sciences, College of Medicine, Lead City University, Ibadan, Nigeria Author
  • Michael Promise Ogolodom Department of Radiography, Faculty of Basic Medical Sciences, Rivers State University, Port Harcourt, Nigeria Author
  • Abdullahi Shuaibu Department of Medical Radiography, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria Author
  • Emmanuel Emeka Ezugwu Department of Radiography and Radiological Sciences, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria Author
  • Olunwayemisi Titi Oyegbata Department of Medical Radiography and Radiation Sciences, College of Medicine, Lead City University, Ibadan, Nigeria Author
  • Misael Ron Industrial Engineer, Specialist in Occupational Health and Hygiene of the work Environment, Specialist in Strategic Management, Doctoral Candidate in Public Health. University of Carabobo, Venezuela Author
  • Oluwafemi Olumide Egbeyemi City Gate Health Diagnostic Services, Ogun State, Nigeria Author

DOI:

https://doi.org/10.56294/evk2025256

Keywords:

Biointerfaces, Medical Devices, Biocompatibility, Implantable Sensors

Abstract

Biointerfaces are strategic components in the design of medical sensors and devices, enabling functional interaction between electronic systems and biological tissues. This article examines their properties, materials, and clinical applications, with a focus on biocompatibility, cellular adhesion, electrical conductivity, and structural stability. Current approaches based on conductive hydrogels, nanocomposites with metal oxides, and intelligent coatings are reviewed, as well as their implications in implantable, wearable, microfluidic, and neural interface technologies. The study also addresses critical challenges such as miniaturization, immune response, and the integration of dynamic, stimulus-activated functions. It concludes that biointerfaces represent a key pathway toward the development of more precise, adaptive, and sustainable medical technologies, whose advancement will depend on interdisciplinary convergence among biomedical engineering, materials science, and emerging clinical needs.

 

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Published

2025-07-16

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Original

How to Cite

1.
Edet Usoro I, Akhigbe RO, Promise Ogolodom M, Shuaibu A, Emeka Ezugwu E, Titi Oyegbata O, et al. Biointerfaces in sensors and medical devices: challenges, materials, and solutions for biological integration. eVitroKhem [Internet]. 2025 Jul. 16 [cited 2025 Jul. 31];4:256. Available from: https://evk.ageditor.ar/index.php/evk/article/view/256